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December 14, 2020  – Cultivation Capital, regularly ranked as one of the most active early-stage venture capital firms in the Midwest, is looking to expand their footprint and their investing activities into the Southeastern United States.

The effort will be led by Co-founder & Managing Director, Cliff Holekamp, who will open a new regional headquarters in Greenville, SC.  Additionally, the firm has hired a new Principal, Alana Mann, who will be based in Nashville, TN.

“We believe that the Southeast is the most logical part of the country for us to add focus and to grow.  The startup community dynamics are similar to those in the Midwest markets where we have thrived,” said Cliff Holekamp.  “In fact, I believe the opportunities are so significant, that I am going myself.”

The growing startup community in Greenville was a draw for Cultivation Capital, as was proximity to major entrepreneurial centers in Charlotte and Atlanta.  Cultivation Capital will open their office in the NEXT on Main innovation center located in ONE City Plaza in Greenville’s Central Business District.

Leaders from NEXT, the SCRA (South Carolina Research Authority), and Hughes Development were all key players in recruiting Cultivation Capital to the Upstate.  “We are delighted to recruit additional capital resources to the region for the benefit of our startup community,” said Ken Brower, Interim, CEO of NEXT.  “Cultivation Capital has an expertise in investing in emerging startup markets and will be a key contributor to our growing entrepreneurial economy.”

Holekamp has been a leading figure in the St. Louis entrepreneurial ecosystem where he helped to grow venture capital investments in that region from $30M in 2011 to $400M in 2019.  He was a board member at several entrepreneurship and economic development organizations including serving as a gubernatorial appointee to the Missouri Development Finance Board.  Additionally, he served as a professor and the Academic Director for Entrepreneurship at Washington University in St. Louis where he led the entrepreneurship program from its infancy to a ranking of #1 in the world in 2019 and 2020 (Inc. Magazine/Poets & Quants ranking).

“I look forward to contributing both my professional and personal efforts to helping build the entrepreneurial ecosystems in South Carolina,” said Holekamp.


About Cultivation Capital

Cultivation Capital is an early-stage venture capital firm investing in software technology, life sciences, and agriculture technology companies.  Since its founding in 2012, the firm has invested in over 150 companies and is recognized as one of the most active early-stage investors in the United States.  For more information, visit